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Food Protein-Induced Enterocolitis Syndrome (FPIES) Defined

Food Protein-Induced Enterocolitis Syndrome (FPIES), sometimes referred to as a delayed food allergy, is a severe condition causing vomiting and diarrhea. In some cases, symptoms can progress to dehydration and shock brought on by low blood pressure and poor blood circulation.

Much like other food allergies, FPIES allergic reactions are triggered by ingesting a food allergen. Unlike a typical food allergy, FPIES allergic reactions are delayed, occurring within hours after eating the trigger allergen. Most children with FPIES have only one or two food triggers, but it is possible to have FPIES reactions to multiple foods. FPIES often develops in infancy, usually when a baby is introduced to solid food or formula.

Learn more about FPIES.