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Q:

6/6/2017
Jackfruit anaphylaxis, Hx? Does it cross with other fruit? Any other cross reactivity?

A:

I have asked Dr. David Fleischer to address your questions. Please see his response below:

"There is one case report of anaphylaxis to jackfruit due to believed cross-reactivity to latex. There are also a few reports of oral allergy symptoms with ingestion of it due to Bet v 1 related proteins.

Jackfruit is related to fig, mulberry and Moraceae family, so these could cross-react.

See below for references to available articles on jackfruit and allergy."

1. Jackfruit anaphylaxis in a latex allergic patient. Wongrakpanich S, Klaewsongkram J, Chantaphakul H, Ruxrungtham K. Asian Pac J Allergy Immunol. 2015 Mar;33(1):65-8. doi: 10.12932/AP0416.33.1.2015. PMID: 25840636 [PubMed - indexed for MEDLINE] Free Article

2. Identification of Bet v 1-related allergens in fig and other Moraceae fruits. Hemmer W, Focke M, Marzban G, Swoboda I, Jarisch R, Laimer M. Clin Exp Allergy. 2010 Apr;40(4):679-87. doi: 10.1111/j.1365-2222.2010.03486.x. PMID: 20447079 [PubMed - indexed for MEDLINE]

3. Allergy to jackfruit: a novel example of Bet v 1-related food allergy. Bolhaar ST, Ree R, Bruijnzeel-Koomen CA, Knulst AC, Zuidmeer L. Allergy. 2004 Nov;59(11):1187-92. PMID: 15461600 [PubMed - indexed for MEDLINE] Free Article

4. Oral allergy syndrome to a jackfruit (Artocarpus integrifolia). Wüthrich B, Borga A, Yman L.
Allergy. 1997 Apr;52(4):428-31. PMID: 9188925 [PubMed - indexed for MEDLINE] Free Article

I hope you find this information helpful.

Regards,
Daniel Jackson, MD

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