The presence or absence of co-existing allergies does not impact how EoE presents or responds to treatment

Published online August 24, 2024

The majority of people who have eosinophilic esophagitis (EoE) frequently have other allergic conditions such as asthma, IgE-mediated food allergies, eczema, or seasonal allergies. However, some people with EoE do not have any history of allergy problems. It is unclear if the presence or absence of other allergy conditions impacts the types of symptoms that a person with EoE has or if it will affect how they respond to treatment.

In a recent article published in The Journal of Allergy and Clinical Immunology: In Practice, Dr. Kohley and the eosinophilic gastrointestinal disorders (EGID) clinical and research team at Arkansas Children’s Hospital and the University of Arkansas for Medical Sciences evaluated 203 children and adolescents seen in their multidisciplinary EGID clinic between 2018 and 2021. The research team reviewed medical records of the EoE patients and separated them into two groups: those with a history of allergy conditions and those without. The research team then investigated the types of symptoms experienced when the patients were diagnosed with EoE, as well as how the groups responded to different EoE treatments.

The research team found that children and adolescents with EoE have similar presenting symptoms and responded similarly to different treatments, regardless of their history of allergy conditions. This is an important finding because it can help guide healthcare providers when evaluating patients who may have EoE, as well as determine how best to treat them after a diagnosis is made.  

The Journal of Allergy and Clinical Immunology: In Practice is an official journal of the AAAAI, focusing on practical information for the practicing clinician.

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