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Oral Immunotherapy Defined

Oral immunotherapy (OIT) refers to the medically supervised therapy of feeding an allergic individual an increasing amount of a food allergen with the goal of increasing the threshold that triggers a reaction. The goal of therapy is to raise the threshold that may trigger a reaction and provide the allergic individual protection against accidental ingestion of the allergen. OIT is not a curative therapy and involves a long-term commitment over several months to years and possibly indefinitely. Individuals who receive OIT will continue to carry epinephrine, read labels closely, etc., and it is not expected that OIT will lead to ingestion of the allergen without limitation. Palforzia® , or peanut allergen flour, is currently the only OIT formulation for children aged 4-17 approved by the Food and Drug Administration (FDA).

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