Food Protein-Induced Allergic Proctocolitis (FPIAP) Defined

Food Protein-Induced Allergic Proctocolitis (FPIAP), is a condition causing inflammation and rectal bleeding in young infants. Much like other food allergies, FPIAP allergic reactions are triggered by ingesting a food allergen. Unlike a typical food allergy, FPIAP allergic reactions may be delayed, occurring within hours after eating the trigger allergen. FPIAP often develops in infancy, sometimes while being breastfed, or when a baby is introduced to formula. Dietary changes for the baby (and for the mother if breastfeeding) are usually necessary to resolve the child’s symptoms. 

Learn more about FPIES and FPIAP.

12/15/2025