Last updated September 2018
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Treatment of Hereditary Angioedema: Replacement therapy or immune modulating medicines pertaining to hereditary angioedema.
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Generic Name
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Brand Name
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Use
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Product Links (if available)
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C1 Esterase Inhibitor (recombinant)
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Ruconest
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Acute angioedema in hereditary angioedema
<84 kg 50 IU/kg; >84 kg 4200 IU-2 vials Given IV
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Ruconest Website
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C1 Inhibitor (human)
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Berinert
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Acute attacks of hereditary angioedema
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Berinert Website
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Cinryze
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To prevent angioedema due to C1 esterase inhibitor deficiency.
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Cinryze Website
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Ecallantide
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Kalbitor
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Acute treatement of angioedema.
From C1 esterase inhibitor deficiency.
Three injections.
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Kalbitor Website
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Icatibant
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Firazyr
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Acute attacks of hereditary angioedema- can be self-administered
1 dose with onset of attack, can repeat in 6 hours, no more than 3 doses in 24 hrs
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Firazyr Website
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| Kallikrein inhibitor- human |
Lanadelumab
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Takhzyro
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12 years and above Type I and II hereditary angioedema
300 mg subcutaneous every 2 weeks; consider every 4 weeks after 6 months |
Takhzyro Website
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