Thank you for your inquiry.
There are three references which will give you the best information we have available on the incidence of anaphylaxis in North America. These are:
1) Wood RA, Camargo CA, Lieberman P, Sampson HA, Schwartz LB, Zitt M, Collins C, Tringale M, Wilkinson M, Boyle J, Simons FER, et al. Anaphylaxis in America: The prevalence and characteristics of anaphylaxis in the United States. Journal of Allergy and Clinical Immunology; 21 October 2013.
2) Lieberman P, Camargo CA, Bohlke K, Jick H, Miller RL, Sheikh A, et al. Epidemiology of anaphylaxis: findings of the American College of Allergy, Asthma and Immunology Epidemiology of Anaphylaxis Working Group. Ann Allergy Asthma Immunol 2006; 97:596-602.
3) Simons FER, Peterson S, Black CD. Epinephrine dispensing patterns for an out of hospital population: a novel approach to studying the epidemiology of anaphylaxis. J Allergy Clin Immunol 2002; 110:647-651.
Thank you again for your inquiry and we hope this response is helpful to you.
Phil Lieberman, M.D.