Q:

6/6/2013
We frequently find patients with increased IgE levels without peripheral eosinophilia (as done in complete blood counts). Kindly guide us for such cases and causes for the same.

A:

Thank you for your inquiry.

Not all causes of elevated IgE are associated with eosinophilia, and in some instances where eosinophilia is present, it may wax and wane. In many instances, the cause of an elevated IgE cannot be determined. For a more detailed look at the potential causes of an elevated IgE, I would refer you to the numerous entries that are posted on our “Ask the Expert” website regarding this issue. You can access these by typing “elevated IgE” into the search box.

Thank you again for your inquiry and we hope this response is helpful to you.

Sincerely,
Phil Lieberman, M.D.

AAAAI - American Academy of Allergy Asthma & Immunology