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Risk of anaphylaxis during oral food challenges

Question:

1/9/2020
I was trying to find the number of OFC performed in the USA as well as the risk of developing an anaphylactic reaction during an OFC. Greiwe et al. had a poster on the Trends in OFC recently at the AAAAI 2019. Akueteet al, reported a risk of anaphylaxis about 2% (lower that what was previously reported).

Do we have an estimate (or what would be the best way) on
- How many OFC are performed in the USA
- What is the current risk of anaphylaxis in patients undergoing OFC?

Answer:

As you know, the risk of anaphylaxis with an OFC is highly dependent on the patient's history and allergy testing.

I asked Dr. David Fleischer to weigh in on your question. His response is as follows:

"I do not know of any national data – there are centers that have published cohorts of their challenges, but there is no national database."

Regards,
Daniel J. Jackson, MD, FAAAAI