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Concentration for intradermal skin testing to local anesthetics

Question:

1/24/2020
In regards to local anesthetic skin testing, is there a reference for a non-irritating percentage for these for skin testing? I am coming up empty on finding a reference.

Answer:

Garvey et al published a very helpful EAACI position paper in 2019. Table 4 from this manuscript contains the information you are seeking. It varies for skin prick testing vs. intradermal testing and also by the local anesthetic.

Garvey LH, Ebo DG, Mertes PM, Dewachter P, Garcez T, Kopac P, Laguna JJ, Chiriac AM, Terreehorst I, Voltolini S, Scherer K. An EAACI position paper on the investigation of perioperative immediate hypersensitivity reactions. Allergy. 2019;74(10):1872-84. Epub 2019/04/10. doi: 10.1111/all.13820. PubMed PMID: 30964555.

Hope this is helpful.

Regards,
Daniel J. Jackson, MD