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Is there any contraindication in starting allergen immunotherapy in patient with adrenal insufficiency? Would there be an issue if a patient was to develop systemic reaction and the adrenal gland is not making appropriate levels of hormones?


It is important to understand the etiology of adrenal insufficiency. For example, is it secondary to corticosteroid use due to severe, uncontrolled asthma, which would be a contraindication to IT? However, if this is not the case, there should not be an issue with response to epinephrine in the case of systemic reactions.

I hope this is helpful.

Daniel J. Jackson, MD, FAAAAI

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