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Allergic contact dermatitis


I was requested to see a patient for desensitization to propylene glycol, a common contact allergen. Are others performing desensitizations to contact allergens in experimental or research protocols?


As you know, the treatment of ACD is to avoid the offending allergen and when avoidance is not possible, to use protective clothing during exposure. I found your question to be interesting so I checked PubMed and In addition to the publication that you cited, which was a small pilot study, the only other literature that I found was a case report of a woman with allergic rhinitis and facial dermatitis who was started on SCIT with cattle dander and a listing for a 2011 study to investigate desensitization for nickel allergy. It doesn't appear that this study was completed.

I hope this information is helpful.

Jacqueline A. Pongracic, MD, FAAAAI