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Treatment of Hereditary Angioedema

Last updated March 2020

 

Treatment of Hereditary Angioedema: Replacement therapy or immune modulating medicines pertaining to hereditary angioedema.

Generic Name

Brand Name

Use

C1 Esterase Inhibitor (recombinant)

Ruconest

Ruconest Website

Acute angioedema in hereditary angioedema

C1 Inhibitor (human)

Berinert

Berinert Website
 

Acute attacks of hereditary angioedema

Intravenous medication to treat acute attacks of hereditary angioedema.

Cinryze

Cinryze Website
 

To prevent angioedema due to C1 esterase inhibitor deficiency.

Intravenous medication to prevent angioedema due to C1 esterase inhibitor deficiency.

 

Haegarda

Haegarda Website

Subcutaneous medication to prevent angioedema due to C1 esterase inhibitor deficiency.

Ecallantide


 

Kalbitor

Kalbitor Website

Acute treatement of angioedema.

From C1 esterase inhibitor  deficiency.

Three injections.

Icatibant





 

Firazyr

Firazyr Website




 

Acute attacks of hereditary angioedema- can be self-administered

1 dose with onset of attack, can repeat in 6 hours, no more than 3 doses in 24 hrs

Kallikrein inhibitor- human

Lanadelumab

 

Takhzyro

Takhzyro Website

 

12 years and above Type I and II hereditary angioedema

300 mg subcutaneous every 2 weeks; consider every 4 weeks after 6 months

 

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