Treatment of Hereditary Angioedema
Last updated January 2024
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Treatment of Hereditary Angioedema: Replacement therapy or immune modulating medicines pertaining to hereditary angioedema.
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Generic Name
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Brand Name
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Use
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Berotralstat
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Orladeyo
Orladeyo Website
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12 years and above as prophylaxis for hereditary angioedema
150 mg once daily
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C1 Esterase Inhibitor (recombinant)
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Ruconest
Ruconest Website
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Acute angioedema in hereditary angioedema
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C1 Inhibitor (human)
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Berinert
Berinert Website
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Acute attacks of hereditary angioedema
Intravenous medication to treat acute attacks of hereditary angioedema.
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Cinryze
Cinryze Website
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To prevent angioedema due to C1 esterase inhibitor deficiency.
Intravenous medication to prevent angioedema due to C1 esterase inhibitor deficiency.
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Haegarda
Haegarda Website
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Subcutaneous medication to prevent angioedema due to C1 esterase inhibitor deficiency.
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Ecallantide
Boxed Warning*
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Kalbitor
Kalbitor Website
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Acute treatement of angioedema.
From C1 esterase inhibitor deficiency.
Three injections.
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Icatibant
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Firazyr
Firazyr Website
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Acute attacks of hereditary angioedema- can be self-administered
1 dose with onset of attack, can repeat in 6 hours, no more than 3 doses in 24 hrs
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Kallikrein inhibitor- human
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Lanadelumab
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Takhzyro
Takhzyro Website
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12 years and above Type I and II hereditary angioedema
300 mg subcutaneous every 2 weeks; consider every 4 weeks after 6 months
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*Boxed Warning – this label indicates that the product, per the FDA, may have serious safety risks. Please speak with your health care provider or pharmacist to learn more about the potential side effects.
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