Selective IgA Deficiency Defined

Selective IgA Deficiency is the most common primary immunodeficiency disease (PIDD). People with this disorder have low or absent levels of a blood protein called Immunoglobulin A (IgA). Levels of IgA mildly below normal will likely not cause problems. IgA protects against infections of the mucous membranes lining the mouth, airways and digestive tract. 

Although individuals with Selective IgA Deficiency do not produce IgA, they do produce all the other kinds of immunoglobulin. This is why many people with IgA deficiency appear healthy or only have mild reoccurring illness such as ear infections, sinus infections, bronchitis and gastrointestinal infections. 

Learn more about Selective IgA Deficiency symptoms, diagnosis, treatment and management.

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