This set of conditions related to chronic inflammation of sinus and contiguous nasal mucosa often co-exists with allergic rhinitis.1 Allergist/immunologist care is associated with improved outcomes.2 Allergy immunotherapy is demonstrated to improve outcomes in patients with concomitant allergic rhinitis.3
Direct outcome evidence
Indirect outcome evidence (immunotherapy)
Many patients with this condition have humoral immunodeficiency, cystic fibrosis, fungal sinusitis, and granulomatous diseases.1 Allergist/immunologists are trained in the evaluation and management of these disorders.4
Diagnostic evidence and indirect outcome evidence (avoidance, pharmacologic, and immunologic therapy)
This is a chronic inflammatory disease with characteristics of allergic inflammation.1 It often co-exists with aspirin sensitivity, asthma, and sinus/nasal polyposis.5, 6 Allergist/immunologists are experts in allergic inflammation and can evaluate and treat both environmental allergy and aspirin sensitivity.4
Diagnostic evidence, indirect outcome evidence (avoidance, pharmacologic, and immunologic therapy)
This is a chronic inflammatory disease with characteristics of IgE and eosinophilic inflammatory response to fungi in sinuses.7, 8 Evaluation involves allergy skin testing and other laboratory testing.9 Management involves medical management, allergen immunotherapy and surgery.9, 10 Allergist/immunologists are experts in the evaluation and management of allergic diseases, including allergy immunotherapy.4
Diagnostic evidence, indirect outcome evidence (pharmacotherapy, immunotherapy)