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Patients & Consumers Conditions En Español Find an Allergist / Immunologist Just for Kids New Research Parent Resources Pollen Levels Publications Request a Speaker School Tools Seniors The Virtual Allergist™ Treatments Donate Now Search by Condition (A-Z) Search by Topic Allergy & Asthma Issues Educational Brochures Elements of Allergy and Asthma Order Public Education Materials Allergy Shots Drug Guide Sublingual Immunotherapy (SLIT)		New Research - September 2009 Laminar air for asthma therapy Summary The investigators in this project examined the effect of temperature-regulated laminar airflow containing a very low particle concentration directed to the breathing zone of asthmatics with mild to moderate allergic asthma during sleep at night. They measured quality of life, expired nitric oxide, and pulmonary functions. Twenty-two patients (mean age 18.8 years) were randomized to either active treatment or placebo for 10 weeks. All patients received both active and placebo treatment with unfiltered air within a two-week washout period between treatments. Medication therapy was not altered. Laminar airflow resulted in an improved mini-AQLQ compared to placebo and also a significantly lower exhaled nitric oxide. These effects were evident after five weeks. There was no change in lung function. The authors concluded that laminar airflow delivered during sleep can have a "positive effect on bronchial inflammation and quality of life in patients with perennial allergic asthma." Reference Pedroletti C, et al. Clinical effects of purified air administered to the breathing zone in allergic asthma: a double-blind randomized cross-over trial. Respiratory Medicine 2009; 103(9):1313-1319. <back>
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