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New Research - August 2009
Factors associated with asthma severity and persistence
Summary:
This article evaluated asthmatics followed in the European Community Respiratory Health Survey II. These patients were followed from 1999 to 2002. One thousand two hundred forty-one adult asthmatics were identified. The GINA Guidelines were used to classify the asthmatics. Factors determining severity and persistence were assessed. Of this database, approximately 30% of the asthmatic subjects suffered from moderate to severe disease. Factors associated with severity and/or persistence were:
- Cladosporium sensitivity was associated with a more than fivefold greater risk of having persistent asthma and asthma severity.
- Persistent asthma was also associated with house dust mite, non-seasonal disease, older age at onset, chronic cough and phlegm production.
- Sensitization to cats increased the risk of severe asthma.
- Smoking was associated with severe asthma in men.
- Rhinitis was associated with severe asthma in women.
Reference:
Cazzoletti L, et al. Asthma severity according to the Global Initiative for Asthma and its determinants: an international study. International Archives of Allergy and Immunology 2010; 151:70-79.
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