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New Research - May 2009Topical application of oat-based products in cereal-allergic patientsThere has been considerable concern about the topical application of potentially allergenic substances in atopic individuals. For example, there has been concern that almond extract contained in one commonly employed lubricant might cause adverse reactions in nut-sensitive patients. A similar concern has been expressed for the presence of Shea butter (produced from a nut) in nut-sensitive individuals. The authors of this article desired to find whether the application of oat-based topical products could cause adverse events in patients allergic to cereal products. To do this they employed Repeated and Maximized Applications (RMA) of oat-containing cosmetics and oat extracts to cereal-allergic atopic adults. It was an open label study in 12 cereal-sensitized atopic adults carried out over 45 days. Open tests and RMA were performed with Rhelba oat-containing cosmetics at Day Zero, Day 10, and from Day 10 to Day 31. Patch and prick tests were also performed at Day 7 and Day 42 with wheat and Rhelba oat extracts as well as the study cream. The authors found no adverse effect due to the RMA of oat-based cosmetics. They concluded that "sensitization to cereal does not increase the risk of allergic reactions to oat-containing cosmetics." Reference
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