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Patients & Consumers Conditions En Español Find an Allergist / Immunologist Just for Kids New Research Parent Resources Pollen Levels Publications Request a Speaker School Tools Seniors The Virtual Allergist™ Treatments Donate Now Search by Condition (A-Z) Search by Topic Allergy & Asthma Issues Educational Brochures Elements of Allergy and Asthma Order Public Education Materials Allergy Shots Drug Guide Sublingual Immunotherapy (SLIT)		New Research - March 2009 Susceptibility to asthma is affected by variations in genes involved with the innate immune system and country living affects this susceptibility The investigators desired to see whether SNPs in CD14, TLR2, TLR4, and TLR9 genes were associated with asthma, and to determine whether or not country living modified these potential associations. They did find that TLR2 and CD14 SNPs were associated with asthma (TLR2) and allergic asthma (CD14). Country living did modify this association. This was especially true for the allergic asthmatic subjects. Reference Smit L, et al. CD14 and toll-like receptor gene polymorphisms, country living and asthma in adults. American Journal of Respiratory and Critical Care Medicine, March 1, 2009; 179(5):363-368. <back>
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