|
||||||||||||||
 |
||||||||||||||
|
|
JACI Highlights - January 2009Effectiveness of SLIT in treating rhinoconjunctivitisRhinoconjunctivitis, or runny nose combined with itchy, watery eyes due to allergies, is on the rise and its burden on sufferers is significant. Poorly controlled symptoms can result in sleep loss and, in children, can cause distraction and sleepiness that contribute to learning problems. A recent study in The Journal of Allergy and Clinical Immunology showed that sublingual immunotherapy (SLIT) using a 300IR dose of five-grass pollens which was taken as a tablet that dissolved under the tongue was effective in treating grass pollen allergic rhinitis in adults. In the study, Wahn et al tested this same dose of five-grass pollen tablets in treating rhinoconjunctivitis in a pediatric population. Two hundred seventy eight children with grass pollen-caused rhinoconjunctivitis were given either a once-daily dose of SLIT tablets that contained active grass allergens or placebo. Treatment began 4 months prior to the start of pollen season and continued throughout the season. For the children who were given the SLIT tablets with active grass allergen, symptoms of sneezing, runny nose, itchy nose, nasal congestion, watery eyes and itchy eyes were significantly improved (by 28%) over those who were given placebo. Those receiving active medication also required significantly less rescue medication for their symptoms than the placebo group. No serious side effects were reported. The authors findings show that 300IR five-grass pollen SLIT tablets is a safe and effective way to treat children and adolescents with grass pollen rhinoconjunctivitis and the relief takes effect in the first treatment season.
|
||||||||||||
|
© 1996-2009 · All Rights Reserved · American Academy of Allergy Asthma & Immunology |
||||||||||||||
