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Patients & Consumers Conditions En Español Find an Allergist / Immunologist Just for Kids New Research Parent Resources Pollen Levels Publications Real Life Stories Request a Speaker School Tools Seniors The Virtual Allergist™ Treatments Search by Condition (A-Z) Search by Topic Allergy & Asthma Issues Educational Brochures Elements of Allergy and Asthma Order Public Education Materials Washington Post Supplement Allergy Shots Drug Guide Sublingual Immunotherapy (SLIT)		SELECTED ARTICLES FROM THE RECENT LITERATURE 2008 11/12/2008 Do corticosteroids plus salmeterol compare to inhaled corticosteroids alone regarding serious asthma-related events? Summary The purpose of this investigation was to determine the incidence of severe asthma-related events (hospitalizations, deaths, et cetera) in persons receiving salmeterol plus inhaled corticosteroids compared with inhaled corticosteroids alone. They evaluated randomized controlled trials that compared inhaled corticosteroids plus salmeterol to inhaled corticosteroids alone in patients with asthma. They evaluated 66 Glaxo Smith Kline trials involving a total of 20,966 participants. They found that salmeterol combined with inhaled corticosteroids diminished the risk for severe exacerbations. However, the combination did not seem to alter the risk for asthma-related hospitalizations, and may not alter the risk for asthma-related deaths or intubations compared with inhaled corticosteroids alone. Reference Bateman E, et al. Meta-analysis: effects of adding salmeterol to inhaled corticosteroids on serious asthma-related events. Annals of Internal Medicine 2008; 149:33-42.   Back
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