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Patients & Consumers Conditions En Español Find an Allergist / Immunologist Just for Kids New Research Parent Resources Pollen Levels Publications Real Life Stories Request a Speaker School Tools Seniors The Virtual Allergist™ Treatments Search by Condition (A-Z) Search by Topic Allergy & Asthma Issues Educational Brochures Elements of Allergy and Asthma Order Public Education Materials Washington Post Supplement Allergy Shots Drug Guide Sublingual Immunotherapy (SLIT)		SELECTED ARTICLES FROM THE RECENT LITERATURE 2008 10/06/2008 Point mutations in the beta receptor affect bronchodilator response Summary The investigators studied 844 single nucleotide polymorphisms (SNPs) in 111 candidate genes in 209 children and their parents. They were looking for an association between SNPs and acute response to inhaled beta agonists. They identified 17 genes, and genotyped 99 SNPs from these genes. They then genotyped 63 snips from 4 genes with significant association with bronchodilator responsiveness. They found that snips from ARG 1 were significantly associated with bronchodilator responsiveness. Reference Litonjua A, et al. ARG 1 is a novel bronchodilator response gene. American Journal of Respiratory and Critical Care Medicine 2008; 178:688-694.   Back
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