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Patients & Consumers Conditions En Español Find an Allergist / Immunologist Just for Kids New Research Parent Resources Pollen Levels Publications Real Life Stories Request a Speaker School Tools Seniors The Virtual Allergist™ Treatments Search by Condition (A-Z) Search by Topic Allergy & Asthma Issues Educational Brochures Elements of Allergy and Asthma Order Public Education Materials Washington Post Supplement Allergy Shots Drug Guide Sublingual Immunotherapy (SLIT)		SELECTED ARTICLES FROM THE RECENT LITERATURE 2008 6/16/2008 Can High-dose Inhaled Steroids be Used Rather Than Oral Steroids for an Exacerbation of Asthma? Summary The authors wished to see if high-dose inhaled corticosteroids were as effective as oral corticosteroids in treating moderate asthma exacerbations. They compared 4000 mcg of fluticasone given in 16 puffs versus 30 mg of prednisone administered orally. Fifty-nine adult patients were randomized and admitted to the study. Both groups had similar improvements in FEV1, sputum plasma protein exudation, and blood eosinophil counts. They concluded that high-dose inhaled fluticasone produced outcomes similar to that of 30 mg of prednisone administered orally. Reference Belda J, et al. European Respiratory Journal 2007; 30:1143-1149.   Back
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