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Patients & Consumers Conditions En Español Find an Allergist / Immunologist Just for Kids New Research Parent Resources Pollen Levels Publications Real Life Stories Request a Speaker School Tools Seniors The Virtual Allergist™ Treatments Search by Condition (A-Z) Search by Topic Allergy & Asthma Issues Educational Brochures Elements of Allergy and Asthma Order Public Education Materials Washington Post Supplement Allergy Shots Drug Guide Sublingual Immunotherapy (SLIT)		SELECTED ARTICLES FROM THE RECENT LITERATURE 2008 11/7/2008 Hypersensitivity to cyclooxygenase inhibitory drugs in children: a study of 164 cases Summary The authors evaluated 164 children who had described 213 reactions to analgesics including paracetamol (acetaminophen), ibuprofen, and/or acetylsalicylic acid (ASA). The majority of the reactions had cutaneous manifestations. There were associated respiratory symptoms, and anaphylaxis occurred as well. Sixty percent reported reactions to ASA, 76.5% to ibuprofen, and 23.2% to paracetamol. 59.1% of patients reacting to nonsteroidals demonstrated cross-reactivity with other nonsteroidals. However, only 10.6% of those sensitive to nonsteroidals reacted to paracetamol. On the other hand, all of the children who reacted to paracetamol also reacted to a nonsteroidal. Reference Hassani A, et al. European Journal of Dermatology 2008; 18(5):561-565.   Back
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