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SELECTED ARTICLES FROM THE RECENT LITERATURE 2008

11/12/2008

The relationship between short-acting beta-agonist use by nebulization and emergency department visits and hospitalizations

Summary
The investigators wished to evaluate the relationship between the type and frequency of short-acting beta-agonists (SABA) use and asthma related outcomes. They looked at emergency room visits and hospitalizations for asthma in members of a large health maintenance organization in southeast Michigan. They evaluated SABA use among patients 5 to 56 years of age enrolled in the HMO. Two thousand fifty-six patients met their study criteria, and 76.3% had used an SABA in the baseline year. They found that SABA nebulizer use was associated with asthma related emergency department visits and hospitalizations. However, the frequency of use of an SABA metered dose inhaler was not associated with these outcomes.

The authors concluded that nebulized SABA use during a three month period was associated with poor asthma outcomes in the form of emergency department visits and hospitalizations.

Reference
Paris J, et al. Relationship between recent short-acting beta-agonist use and subsequent asthma exacerbations. Annals of Allergy, Asthma, and Immunology 2008; 101(5):482-487.

 

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