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Patients & Consumers Conditions En Español Find an Allergist / Immunologist Just for Kids New Research Parent Resources Pollen Levels Publications Real Life Stories Request a Speaker School Tools Seniors The Virtual Allergist™ Treatments Search by Condition (A-Z) Search by Topic Allergy & Asthma Issues Educational Brochures Elements of Allergy and Asthma Order Public Education Materials Washington Post Supplement Allergy Shots Drug Guide Sublingual Immunotherapy (SLIT)		SELECTED ARTICLES FROM THE RECENT LITERATURE 2008 September 15, 2007 Predictions of eosinophilic esophagitis in patients with dysphagia Summary Background - Dysphagia (Dp) is a common manifestation of eosinophilic esophagitis (EE) but also occurs in a number of other disorders. Findings - Prasad et al of the Mayo Clinic carried out mid-esophageal biopsies in 222 adults with Dp and either 1) gross endoscopic findings suggestive of EE or 2) no obvious cause of Dp on gross endoscopic exam. In these patients 15% had pathologic evidence of EE, including 10% of those with grossly normal findings in endoscopy. Pathologic evidence of EE was likely in younger individuals, absence of the use of PPI drugs and food impaction for more than 5 minutes. Reference Am J Gastroenterology 2007; August 31, E pub Editor's Comments These findings suggest that about one in 10 adults with unexplained solid food Dp have pathologic evidence of EE (>20 eosinophil per HPF in a mid-esophageal biopsy). If confirmed, this findings has important therapeutic implications since there are promising on-going and developing treatments for EE.   BACK
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