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Patients & Consumers Conditions En Español Find an Allergist / Immunologist Just for Kids New Research Parent Resources Pollen Levels Publications Real Life Stories Request a Speaker School Tools Seniors The Virtual Allergist™ Treatments Search by Condition (A-Z) Search by Topic Allergy & Asthma Issues Educational Brochures Elements of Allergy and Asthma Order Public Education Materials Washington Post Supplement Allergy Shots Drug Guide Sublingual Immunotherapy (SLIT)		SELECTED ARTICLES FROM THE RECENT LITERATURE 2008 December 10, 2007 Nature versus Nurture: The Impact of Each on the Development of Atopic Dermatitis Summary Danish investigators utilized a birth cohort of 11,515 pairs of twins via the Danish Twin Registry. The birth cohorts were enrolled from 1953 to 1982. The main object of the study was to establish the relative roles of inheritance verus environment related to the impact on the development of atopic dermatitis. The overall lifetime prevalence of atopic dermatitis in this cohort was 7.3%. A co-twin of an affected identical twin had a sevenfold increased risk of developing atopic dermatitis. If the twins were fraternal, this risk was threefold (the risk was compared with that of the general population). Genes contributing to the susceptibility of atopic dermatitis were the same in both male and female subjects. Editor's Comments The authors found that genes accounted for 82%, and non-shared environmental factors accounted for 18% of the individual's susceptibility to develop this condition. Reference Thomsen SF, et al. Importance of genetic factors in the etiology of atopic dermatitis: a twin study.   BACK
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