Find An Allergist / Immunologist | Pollen Levels | Journal of Allergy and Clinical Immunology | Annual Meeting   Contact    About AAAAI    Search
Patients & Consumers Conditions En Español Find an Allergist / Immunologist Just for Kids New Research Parent Resources Pollen Levels Publications Real Life Stories Request a Speaker School Tools Seniors The Virtual Allergist™ Treatments Search by Condition (A-Z) Search by Topic Allergy & Asthma Issues Educational Brochures Elements of Allergy and Asthma Order Public Education Materials Washington Post Supplement Allergy Shots Drug Guide Sublingual Immunotherapy (SLIT)		SELECTED ARTICLES FROM THE RECENT LITERATURE 2008 September 25, 2007 Budesonide in breast milk Summary Background - Maintenance treatment with inhaled corticosteroids (ICS) is frequently required by asthmatic women who are also nursing their infants. Does such ICS used by the mother get into breast milk to a degree where it may adversely affect the infant? Findings - Falt et al assessed budesonide (Bud) concentrations in breast milk and blood plasma of nursing women being treated with inhaled Bud (200-400 mcg b.i.d.). Breast milk Bud levels reflected that in maternal plasma with the average milk/plasma Bud ratio of about 0.45. The estimated Bud dose ingested daily by the infant was about 0.3% of the daily maternal dose. Bud levels in the infant plasma were below the quantifiable limit. The authors concluded that maintenance inhaled Bud treatment of 200-400 mcg b.i.d. results in a negligible exposure of their nursing infants to Bud. Reference J Allergy Clin Immunol 9/6/07, E pub Editor's Comments These findings are fairly reassuring for asthmatic women who wish to nurse their infants. Of course, one cannot yet say whether the same reassurance applies in the small minority of asthmatic women who need sizably higher doses of ICS for asthma control.   BACK
		© 1996-2010 · All Rights Reserved · American Academy of Allergy Asthma & Immunology Disclaimers and Contact Information · Site Map