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Teaching Curriculum: Total and Allergen-Specific IgE

Priorities:
Pediatrics 3, Internal Medicine 4
Family Practice 4, Student 4

OBJECTIVES
Upon completion the rotator should be able to:

  1. List ranges of normal serum IgE levels according to age:
    1. newborn
    2. one-year-old child
    3. ten-year-old child
    4. adult
  2. Discuss sensitivity and specificity of total serum IgE level as a screening test for patients with allergic disease
  3. Describe in vitro techniques available to assay allergen specific IgE
  4. Describe how the results of in vitro allergen-specific IgE assays are reported in clinical practice
  5. List conditions in which levels of total serum IgE are elevated; include examples of atopic and non-atopic diseases

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