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JACI Highlights - March 2007
Untersmayr et al – Incomplete digestion of codfish represents a risk factor for anaphylaxis in allergic patients
Fish represents one of the most important causes of food allergy. In the March 2007 issue of the Journal of Allergy and Clinical Immunology, Untersmayr and colleagues study the absorption of fish proteins and the reactivity of fish allergic patients to codfish. They found that gastric digestion has an important gate-keeping function for fish allergens. If digestion is impaired, these allergens can pass into the intestine and are able to elicit severe allergic symptoms. Hindered digestion puts fish allergic patients at risk to develop severe allergic reactions.
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