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JACI Highlights - February 2007

Baynam et al - Parental smoking impairs vaccine responses in allergic children

In the February 2007 issue of the Journal of Allergy and Clinical Immunology, Baynam and colleagues investigate the hypothesis that parental smoking may effect the response of infants to vaccinations. The authors found that parental smoking can suppress immune response to vaccines in children. These findings may have implications for infant vaccination in countries with high smoking rates. It may also have broader implications in relation to environmental toxicology as it demonstrates specific mechanisms through which the developing immune system may be differently sensitive to low level toxic exposures.

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