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JACI Highlights - February 2007

Arshad et al - Prevention of allergic disease during childhood by allergen avoidance - The Isle of Wight prevention study

In the February 2007 issue of the Journal of Allergy and Clinical Immunology, Harshard and colleagues evaluated the effect of reduction in food and house-dust mite allergen exposure in infancy in preventing asthma and allergy. Early life allergen exposure may increase the risk of childhood allergy, but the protective effect of reduction in allergen exposure remains uncertain. The authors found that allergic diseases can be reduced in the first 8 years of life by combined food and house-dust mite allergen avoidance in infancy. Therefore, strict food and house-dust mite allergen avoidance should be considered for prevention of allergy in high-risk infants.

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