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JACI Highlights - November 2006

Garcia-Robaina et al - Successful treatment of mite allergic asthma with modified extracts of D. pteronyssinus and D. farinae in a double-blind placebo-controlled study

House dust mites are one of the most common sources of indoor allergens worldwide. In subtropical latitudes, most allergic individuals are sensitized to house dust mites. In the November 2006 issue of the Journal of Allergy and Clinical Immunology, García-Robaina and colleagues studied the efficacy and safety of immunotherapy with mite extracts in patients with mite allergic asthma. The authors found that immunotherapy with a mixture of modified allergen extracts of two types of house dust mite is safe and efficacious to treat mite allergic asthma. This immunotherapy modifies the natural course of the illness. It improves all clinical outcomes measured and prevents the worsening of specific bronchial hypersensitivity.

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