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JACI Highlights - July 2006
Baatenburg de Jong et al - Normal lung function in children with mild to moderate persistent asthma well controlled by inhaled corticosteroids
In the July 2006 issue of the Journal of Allergy and Clinical Immunology, Baatenburg de Jong and colleagues study the lung function in children with mild-to-moderate persistent asthma. International guidelines on the diagnosis and management of childhood asthma emphasize the importance of assessing its severity with objective measures of lung function. They found that the majority of children with stable, mild-to-moderate asthma and good adherence to inhaled corticosteroid therapy usually have normal lung function and little or no bronchodilator response. This calls into question the use of reduced lung function and presence of bronchodilator response as inclusion criteria for clinical trials in childhood asthma.
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