Anaphylaxis demographics studied in Florida emergency departments

Published Online: June 29, 2011

Previous population-based analyses of emergency department (ED) visits for anaphylaxis in the US primarily described small populations in northern latitudes.

In an upcoming issue of The Journal of Allergy and Clinical Immunology (JACI), Harduar-Morano, et al conducted a study including all Florida EDs and identified 2,751 patients with anaphylaxis using International Classification of Diseases ninth revision Clinical Modification (ICD-9-CM) codes and a unique ICD-9-CM based diagnostic algorithm. Anaphylaxis patients were most often boys ages 0-4 and women ages 15-54. The age-adjusted ED visit rate was 6.6/100,000 males/year and 8.7/100,000 females/year.

The overall rate (7.6/100,000) is lower than other US ED population-based studies possibly related to southern latitude or because case identification was not based on medical record review. Males and Blacks were 20% and 25%, respectively, more likely to have a food trigger than females and Whites. Venom-induced anaphylaxis was more likely in August-October, (confirming previous observations that insect sting anaphylaxis has a seasonal pattern) and occurred more often among whites, males and older individuals. Children were less likely than those >70 years to have medication-induced anaphylaxis. The prevalence of particular anaphylaxis triggers was different in ED versus hospitalized patients. Demographic description of anaphylaxis patients with unknown triggers was reported; how these patients affect currently reported anaphylaxis risk factors is unclear.


The Journal of Allergy and Clinical Immunology (JACI) is the official scientific journal of the AAAAI, and is the most-cited journal in the field of allergy and clinical immunology.

AAAAI - American Academy of Allergy Asthma & Immunology