Thank you for your inquiry.
A metallic taste has been noted to be a prodrome of anaphylactic events along with other symptoms such as itching and paresthesias of the palms and soles, sweating, headache, or disorientation (1). However, the full-blown episode of anaphylaxis occurs shortly after these earlier noted manifestations. I am not aware of isolated episodes of metallic taste, not followed by a full-blown episode of anaphylaxis, being noted as a risk factor for future events. Thus, I know of no evidence to support your patient’s metallic taste as placing her at increased risk of an anaphylactic episode in the future. That is, metallic taste has been noted to occur early in the course of an event, but never as an isolated indication that that may occur in the future. I also could not find any indication that isolated episodes of metallic taste would place her at risk of an anaphylactic episode via a literature search.
Thank you again for your inquiry and we hope this response is helpful to you.
1. Ring J, et al. History and classification of anaphylaxis. In: anaphylaxis: Novartis Foundation, published by Wiley in 2004, Page 8.
Phil Lieberman, M.D.