The Prescribing information for Zyflo CR includes:
"Assess hepatic function enzymes prior to initiation of ZYFLO CR, monthly for the first 3 months, every 2-3 months for the remainder of the first year, and periodically thereafter."
In a patient with no suggestion of hepatotoxicity, for routine surveillance, how often do you recommend the "periodically thereafter" be. I was unable to find any specific guidance in the literature. Thank you.