Converting SCIT antigen to SLIT antigen. A patient has started SCIT and after purchasing the antigen for SCIT, is requesting to initiate SLIT instead. Is there any protocol in converting/diluting her already-purchased SCIT antigen into SLIT? Thanks!


Thank you for your inquiry.

We had a recent somewhat similar inquiry submitted to our website regarding the use of subcutaneous immunotherapy vaccines in the performance of sublingual immunotherapy. I copied the portion of the entry below that deals with your inquiry.

Quote: "At this time, there is no oral immunotherapy for respiratory allergy approved in the United States. The extracts that we are presently using for subcutaneous immunotherapy are not appropriate for use in oral immunotherapy because they have not been tested in this regard, and therefore we do not know what the appropriate doses or protocol would be. So, at this time, in my opinion, it is inappropriate to use them for oral immunotherapy."

Thank you again for your inquiry and we hope this response is helpful to you.

Phil Lieberman, M.D.

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AAAAI - American Academy of Allergy Asthma & Immunology