Thank you for your inquiry.
I know of no studies that have looked specifically at this issue, but we do know that the most important variable in regards to the efficacy of immunotherapy in general is thought to be the total dose administered (not the frequency of dosing). Therefore I don't feel there would be any difference in efficacy between the dosage regimens you described.
Thank you again for your inquiry and we hope this response is helpful to you.
Phil Lieberman, M.D.