47 year-old male with long standing history of AR, asthma, eczema, intermittent lower GI cramping/discomfort. In addition to his symptoms he has elevated IgE(1819), borderline low WBC for years (around 3.0 k/Ul). He has also had slightly elevated eosinophils but all under 600. Recent colonoscopy with diverticulosis, focal erosion and hemorrhage on sigmoid colon via biopsy no malignancy or dysplasia. On CBC . He has seen GI, Rheumatology, and Hematology. Various blood tests WNL (HIV, SPEP, ANCA, IgG, IgA, IgM, various autoantibodies). His most recent CRP is elevated at 25.7 mg/L. He has no recurrent infections aside from one episode of epididymitis (etiology?) and a couple episodes of diverticulitis. He is currently on Xolair (off inhaled steroids), AIT, Lexapro, SABA PRN, Veramyst, antihistamines PRN, Various topical steroids (derm RX). GI started Apriso to see if would help GI sx despite negative w/u for inflammatory bowel disease. Eczema remains out of control. Is there something I'm missing that may tie the GI complaints, low WBC and severe atopy eczema together?