We have a case of a 5 year-old boy with Acute Disseminated Encephalomyelitis (ADEM) admitted on the wards. He has had bee sting allergy (generalized hives, edema of face and lips last year). Parents were contemplating Allergen Immunotherapy therapy for him for his bee sting allergy in future. Now they are asking if this therapy may trigger/flare up the ADEM. I was not able to find any literature to answer this question. Would you give us your thoughts on this? Thanks.


Thank you for your inquiry.

I am not aware of, and could not find in the literature, any reason to withhold venom immunotherapy in a patient who had an episode of acute disseminated encephalomyelitis. Thus I think that the most reasonable conclusion is that a previous episode of ADEM would not preclude the administration of venom immunotherapy.

Thank you again for your inquiry and we hope this response is helpful to you.

Phil Lieberman, M.D.

Ask A Question

Healthcare Professionals: If you can’t find what you are looking for, please send us your question.

Due to the number of questions submitted to Ask the Expert, we are experiencing a significant delay in responses at this time.

Ask now

AAAAI - American Academy of Allergy Asthma & Immunology