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Omalizumab for Netherton Syndrome

Question:

9/12/2017
Are you aware of any benefit or harm of using xolair or Dupilumab in Nethertons Syndrome?

Answer:

We found no literature on dupilumab in Netherton syndrome. We found a single case report in which omalizumab decreased allergic skin symptoms and mucosal symptoms referenced below.

Yalcin AD. A case of Netherton syndrome: successful treatment with omalizumab and pulse prednisolone and its effects on cytokines and immunoglobulin levels. Immunopharmacol Immunotoxicol 2015; 1-5.

Patricia McNally, MD, FAAAAI