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November 2006 QUIZ OF THE MONTH . . .

Chronic idiopathic urticaria (CIU) is a common clinical problem often frustrating to the patient and treating physicians. Which of the statements below about CIU are true or false?

  1. In almost all cases of CIU the urticaria remits completely within 5 years of onset.
  2. There is an increased incidence of thyroid autoimmunity in patients with CIU.
  3. The skin wheals which are prominent in CIU are due to of anti-desmosome antibodies at the dermal-epidermal junction.
  4. In a sizable percentage of patients with CIU the serum contains antibodies which react with the high-affinity IgE receptor.
  5. Cyclosporine treatment frequently controls CIU, which has not responded to anti-histamine therapy.

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