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August 2006 QUIZ OF THE MONTH . . .

The hyper-immunoglobulin E syndrome (HIES) should be considered in the differential diagnosis in a patient with extensive eczema and a very elevated serum IgE level. Which of the following statements about the HIES are true or false:

  1. The HIES is characterized by frequent skin abscesses, often caused by Staph aureus infection
  2. The autosomal recessive form of HIES is characterized by skeletal and dental abnormalities
  3. The autosomal dominant form of HIES is characterized by frequent bouts of severe molluscum contagiosum
  4. The Churg-Strauss Syndrome (CSS) can be distinguished from the HIES by the presence of vasculitis in the CSS
  5. Chronic asthma is present in most cases of both the HIES and of allergic bronchopulmonary aspergillosis (ABPA)


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