November 2005 QUIZ OF THE MONTH . . .
Although treatment of asthma with inhaled corticosteroids (ICS) is generally safe, there are concerns about potential adverse systemic effects of chronic ICS therapy. Which of the statements below are true or false?
The major source for systemic absorption of most ICS agents is the ICS swallowed during the inhalation procedure.
The likelihood of systemic effects of an ICS agent is related to the binding affinity of that agent to corticosteroids receptors.
The higher the degree of binding of an ICS agent to plasma proteins, the more likely there will be adverse systemic effects.
Chronic treatment of growing children with ICS results in a transient reduction in growth velocity.
In almost all cases, treatment with oral anti-candida therapy (swish and swallow) eliminates the hoarseness associated with chronic ICS therapy.
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