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NOVEMBER 2004 QUIZ OF THE MONTH . . . Which of the statements about hereditary angioedema (HAE) or its acquired variants are true or false?
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NOVEMBER 2004 QUIZ OF THE MONTH . . .
Which of the statements about hereditary angioedema (HAE) or its acquired variants are true or false?
- HAE is characterized by decreased serum levels of C1q, C3 and C4 components of complement.
- Bradykinin is a major mediator of the angioedema in HAE.
- All symptomatic HAE patients have decreased serum levels of the C1 inhibitor (C1 INH) as determined by immunoassay.
- The clinical improvement during treatment of HAE with altered androgens (e.g. danazol) requires a normalization in serum levels of the C1 inhibitor (C 1 INH).
- An acquired variant of hereditary angioedema is associated with increased serum levels of anti-C1 INH antibodies.
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