SELECTED ARTICLES FROM THE RECENT LITERATURE 2008 5/6/2008 Factors Correlating with a Positive Aspirin Challenge in Patients with Suspected Aspirin Related Respiratory Tract Disease Summary These investigators analyzed factors which might predict a positive oral aspirin challenge in patients with suspected aspirin exacerbated respiratory disease. A total of 243 patients underwent oral aspirin challenge. Gender, the presence of atopy, or the number of sinus infections per year did not correlate with positive challenges. Increasing frequency of previous NSAID respiratory reactions, severity of these reactions, reactions requiring hospitalization, age younger than 40, and poor sense of smell increased the chances of a positive oral challenge. Reference Dursun A, et al. Predicting outcomes of oral aspirin challenges in patients with asthma, nasal polyps, and chronic sinusitis. Annals of Allergy, Asthma, and Immunology 2008; 100(5):420-425.   © Copyright 1997-2008 American Academy of Allergy, Asthma and Immunology All rights reserved