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December 19, 2007 Early Childhood Eczema Predicts SensitizationSummary The authors concluded that in non-sensitized children, eczema, but not wheeze, asthma, or rhinitis, was a predictor for subsequent development of sensitization. Reference
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SELECTED ARTICLES FROM THE RECENT LITERATURE 2007December 19, 2007
Early Childhood Eczema Predicts Sensitization
Summary
This childhood asthma prevention study evaluated children with a family history of asthma. These children were assessed with total serum IgE, wheeze, asthma, eczema, and rhinitis evaluations at ages 18 months and 5 years. At 18 months, children who were non-sensitized (N = 375), were examined for subsequent sensitization at 5 years. Among children who were non-sensitized at age 18 months, the presence of eczema, but not wheeze, asthma, or rhinitis, was an independent predictor of the onset of sensitization by 5 years. In addition, among children who were asymptomatic at age 18 months, sensitization to any allergen at 18 months was an independent predictor for the presence of wheeze, asthma, and rhinitis, but not for the development of eczema at age 5 years.The authors concluded that in non-sensitized children, eczema, but not wheeze, asthma, or rhinitis, was a predictor for subsequent development of sensitization.
Reference
Almqvist C, et al. Early predictors for developing allergic disease and asthma: examining separate steps in the allergic march. Clinical and Experimental Allergy 2007; 37:1296-1302.
